How To Beat The GLP1 Side Effects

Let’s be real—starting GLP1 medications like Ozempic, Wegovy, or Mounjaro can feel like a game-changer. You're finally on a plan that helps with weight loss or diabetes, and you’re hopeful. But then the nausea hits. Maybe it's constipation, or diarrhea, or just feeling full all the time. These side effects are common, and you're not alone if you're wondering if it's worth it.

I've been there, and I know how frustrating it is when you're trying to do something good for your health, but your body fights you with every bite or sip. But here's the truth: it doesn't have to stay that way. There are practical, gentle ways to help your body adjust—ways that work and keep you feeling like yourself again.

Let’s walk through it, one step at a time.

How I Almost Quit—and Why I Didn’t

When I first started GLP1 meds, I thought something was wrong with me. Everyone online seemed to be dropping pounds and feeling great. Meanwhile, I was dizzy, bloated, and constantly nauseous. I couldn’t get through a meal without feeling miserable. I even skipped social plans because I wasn’t sure I could eat without getting sick. It felt lonely. But then I realized—my experience wasn’t unusual. I just hadn’t figured out how to manage it yet. Once I stopped comparing and started listening to my body, things slowly turned around. It wasn’t perfect, but it was manageable—and worth it.

First, Why Do These Side Effects Happen?

GLP1 receptor agonists work by slowing down how fast your stomach empties. That helps you feel full longer, but it's also why you might get bloated or nauseous. The exact mechanism helps regulate your appetite and blood sugar, which is excellent for weight loss and managing diabetes, but your digestive system needs time to catch up.

Most side effects—like nausea, constipation, or diarrhea—are most intense when you start or when your dose increases. The good news? Your body can and usually does adjust. But in the meantime, you’ll need some solid tools to manage the rough patches.

Hydration is Crucial, But It’s Not Just About Water

Everyone says “drink more water,” and yes, that’s important. But here’s what they don’t say: drinking plain water when you're nauseous is not easy. The trick is to switch to electrolytes—the kind with no sugar and no junk. They’re much gentler on your stomach and way more effective at keeping you hydrated, especially when your body is dealing with GI issues.

Electrolytes also help you bounce back faster if you’ve had a bout of diarrhea or are struggling with lightheadedness. Think of it as hydration with a purpose, not just gulping down bottles of water and hoping for the best. I love Liquid IV and Hydrant!

Digestive Enzymes: The Unsung Hero When You’re Too Full

One of the weirdest GLP1 side effects? Feeling overly full even after a tiny meal. It's uncomfortable and makes eating feel like a chore. That's where digestive enzymes come in. They help break down food more efficiently, especially proteins and fats, so your stomach doesn't have to work as hard.

I started taking a digestive enzyme supplement with meals, especially dinner, and it completely changed how I felt. No more heavy, “food just sitting there” feeling. It’s a small thing with a big impact.

Let’s Talk About Nutrition—And Hair

When your appetite is all over the place, getting the nutrients your body needs is hard. That's why a solid multivitamin is non-negotiable. Not just any gummy from the supermarket shelf—a real, doctor-formulated option that fills in the gaps when you're eating less.

Some people also notice hair shedding on these meds. It’s not common, but it can happen, especially if you’re losing weight quickly and not getting enough protein or iron. I added a hair support supplement that included biotin and collagen and a hair care system from Vegamour which helped with shedding, which helped. Hair is a personal, emotional thing—don't ignore it if you start noticing changes.

Constipation Is Real—Magnesium Can Help

GLP1 meds slow down digestion, and that often means constipation. It’s more than uncomfortable; it can mess with your entire day. Increasing fiber is helpful, but if your appetite’s low, that’s hard to do consistently.

So, I tried magnesium, and it changed everything. Not only did it help get things moving again, but it also made me feel more relaxed. GLP1 meds can make you feel a little tense, especially at night. Magnesium gave me better sleep and calmer evenings. If you're going to try anything for constipation, start here. It's gentle and safe and helps with so much more than just digestion.

You’re Not Failing—You’re Adjusting

I wish more people talked about how emotional this adjustment can be. When your stomach doesn't feel right, everything feels harder—meals, socializing, and even just going about your day. But managing side effects doesn't mean the medication is “bad” or that it’s not right for you. It just means your body needs a little support while it adjusts.

I used to think I had to push through and just wait it out. But once I added a few of these tools—electrolytes, digestive enzymes, magnesium, a multivitamin—I felt in control again. That shift made all the difference.

Mochi Health Is a Game Changer

Mochi Health is a great option if you're struggling and don't know where to start. They don't just hand you a prescription and send you on your way. They guide you through the whole journey—including how to handle the rough parts. You get real answers from people who've been there, not just generic advice.

They understand that GLP1 side effects are real and that managing them takes more than willpower. It takes support, innovative tools, and a team that knows what works.

Disclaimer: This is not medical advice, but personal tips from my experience. Always consult your healthcare provider before starting any medication. This post contains affiliate links to products that I get a commission on. These are products that I have purchased myself and love.